(2) Cancer-associated Carbohydrate Antigens
نویسندگان
چکیده
منابع مشابه
Cancer-Associated Carbohydrate Antigens as Potential Biomarkers for Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is one of the most common human malignancies. Therefore, developing the early, high-sensitivity diagnostic biomarkers to prevent HCC is urgently needed. Serum a-fetoprotein (AFP), the clinical biomarker in current use, is elevated in only ~60% of patients with HCC; therefore, identification of additional biomarkers is expected to have a significant impact on publi...
متن کاملCarbohydrate differentiation and cancer-associated antigens detected by monoclonal antibodies.
action was the pluripotential haemopoietic stem cell (CFUS ) . Whenever they were tested, free glycosaminoglycan chains were unable to reproduce P-D-xyloside influences on cell behaviour. On the basis of the cited biochemical evidence it seems likely that the xyloside effects are mediated through alterations in surface membrane proteoglycans. Most probably the xyloside-induced changes follow fr...
متن کاملTumor Associated Carbohydrate Antigens in Targeted Therapy
Tumor associated carbohydrate antigens (TACAs) are a class of glycans with important structural and signaling functions playing a major role in cell proliferation, differentiation, and apoptosis relevant to oncology. Tumor cells expressing TACAs influence prognosis and survival of cancer patients. Careful consideration must be given to structural aspects during rational design of small molecule...
متن کاملHelianthus annuus Leaf Ameliorates Postprandial Hyperglycaemia by Inhibiting Carbohydrate Hydrolyzing Enzymes Associated with Type-2 Diabetes
Background: Diabetes mellitus is a chronic disease. Decreasing postprandial hyperglycemia by retarding glucose absorption through inhibiting carbohydrates digesting enzymes (α-amylase and α-glucosidase) is one of many approaches used for the management of this disease. This study was aimed at evaluating the normoglycaemic potential of Helianthus annuus leaf. Methods: The effect o...
متن کاملTumor-associated antigens in breast cancer.
The targets for the immune system are antigens present on cancer cells; however, many are not cancer-specific and may also be found on normal tissues. These antigens are often products of mutated cellular genes, aberrantly expressed normal genes, or genes encoding viral proteins. Vaccines constitute an active and specific immunotherapy designed to stimulate the intrinsic antitumor immune respon...
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ژورنال
عنوان ژورنال: Japanese Journal of Medicine
سال: 1988
ISSN: 0021-5120,1881-123X
DOI: 10.2169/internalmedicine1962.27.98